JOURNAL CLUB
07.01.2010 8:30AM (Clara):
RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation (Cell 2009)
( link )
05.01.2010 8:30AM (Vasco):
L1 retrotransposition in human neural progenitor cells (Nature 2009)Download file
(...)
27.08.2009 8:30AM (Nadine):
To be announced...
25.08.2009 8:30AM (Clara):
To be announced...
13.08.2009 8:30AM (Vasco):
To be announced...
11.08.2009 8:30AM (Nadine):
To be announced...
30.07.2009 8:30AM (Catarina):
Another look on: "Alternative Splicing Regulates Activation-Induced Cytidine Deaminase (AID): Implications for Suppression of AID Mutagenic Activity in Normal and Malignant B-Cells" ( link )
"Active nuclear import and cytoplasmic retention of activation-induced deaminase" Patenaude, Noia et al (2009) NATURE STRUCTURAL & MOLECULAR BIOLOGY ( link ) (Postponed)
28.07.2009 8:30AM (Daniel):
"AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity" Download file
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16.07.2009 8:30AM (Thiago):
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14.07.2009 8:30AM (Catarina):
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02.07.2009 8:30AM (Vasco):
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30.06.2009 8:30AM (Clara):
"RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci" Hewitt, Skok et al. (2009) Nature Immunology Download file
18.06.2009 8:30AM (Thiago):
"Control of Stochasticity in Eukaryotic Gene Expression" Raser & O'Shea (2004) Science Download file
16.06.2009 8:30AM (Daniel):
...
04.06.2009 8:30AM (Nadine):
"Haploinsufficiency of Activation-Induced Deaminase for Antibody Diversification and Chromosome Translocations both In Vitro and In Vivo" Sernández IV, de Yébenes VG, Dorsett Y, Ramiro AR, (2008) PLoS ONE 3(12): e3927 ( link )
02.06.2009 8:30AM (Clara):
"Locus ‘decontraction’ and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene" Roldán and Skok, Nat Immunol. 2005 January; 6(1): 31–41. ( link )
21.05.2009 8:30AM (Vasco):
"Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity" Cell (2008) 135, 1130–1142 link to PubMed
19.05.2009 8:30AM (Thiago):
"Stochastic Gene Expression in a Single Cell" Science (2002) 297, 1183 Elowitz et al. 2002
07.05.2009 8:30AM (Catarina):
Announced By e-mail...
05.05.2009 8:30AM (Daniel):
"Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression" Int J Cancer (2008) 123(12):2735-40 link to PubMed
23.04.2009 8:30AM (Nadine):
"Tissue-specific sensitivity to AID expression in transgenic mouse models" Gene. (2006) 377:150-8 link to PubMed
21.04.2009 8:30AM (Clara):
"Targeted inhibition of V(D)J recombination by a histone methyltransferase." Osipovich, O., R. Milley, et al. (2004). Nat Immunol 5(3): 309-16. Link to pdf
09.04.2009 8:30AM (Vasco):
"Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed."Alexander, M. K., S. Mlynarczyk-Evans, et al. (2007). J Cell Biol 179(2): 269-76. link to PubMed
and: "X chromosome choice occurs independently of asynchronous replication timing." Gribnau, J., S. Luikenhuis, et al. (2005). J Cell Biol 168(3): 365-73. link to PubMed
and: "Asynchronous replication of imprinted genes is established in the gametes and maintained during development." Simon, I., T. Tenzen, et al. (1999). Nature 401(6756): 929-32.
Link to pdf
07.04.2009 8:30AM (Catarina):
"Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination"Vuong, 2009
26.03.2009 8:30AM (Daniel):
Part II
24.03.2009 8:30AM (Daniel):
Part I of: Nonaka, T., T. Doi, et al. (2009). "Carboxy-terminal domain of AID required for its mRNA complex formation in vivo." Proc Natl Acad Sci U S A 106(8): 2747-51. PubMed link
19.03.2009 8:30AM (Nadine):
"Activation-Induced Cytidine Deaminase Links Between Inflammation and
the Development of Colitis-Associated Colorectal Cancers" Endo et al, Gastroenterology (2008)
10.03.2009 8:30AM (Clara):
"A role for the IgH intronic enhancer Emu in enforcing allelic exclusion" (Li and Eckhardt, JEM2008)
05.03.2009 8:30AM (Vasco):
"AID can restrict L1 retrotransposition suggesting a dual role in innate and adaptive immunity."
MacDuff, 2009 (link)
and: "Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination"Vuong, 2009
19.02.2009 8:30AM (Catarina, 2nd part):
"Rate of Increase in Circulating IL-7 and Loss of IL-7R Expression Differ in HIV-1 and HIV-2 Infections: Two Lymphopenic Diseases with Similar Hyperimmune Activation but Distinct Outcomes"
Albuquerque 2007
and: "Efficient Thymopoiesis Contributes to the Maintenance of Peripheral CD4 T Cells during Chronic Human Immunodeficiency Virus Type 2 Infection" Gautier 2007
12.02.2009 8:30AM (Daniel):
Arakawa, 2007
15.01.2009 8:30AM (Daniel):
Muto, 2006
13.01.2009 8:30AM (Nadine):
Takai, 2008
08.01.2009 8:30AM (Clara):
Liang, 2004
--2008--
04.11.2008 8:30AM (Clara):
Nguyen, 2007 (PMID: 18045541) Comment to Nguyen, 2007
15.10.2008 8:30AM (Clara):
Calado, 2007
06.10.2008 8:30AM
Nepal, 2008 Complementary Honjo, 2007(Nadine)
02.10.2008 8:30AM
Yoo, 2007 (Daniel)
25.09.2008 8:30AM
Virgina, 2006 (Daniel)
23.09.2008, 8:30AM
Voss, 2006 Commented by: Borst and Genest, 2006(Clara)
18.09.2008, 8:30AM
Fagarasan, 2001(Clara)
16.09.08, 8:30AM
Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease. PLoS ONE. 2008 Aug 21;3(8)(Vasco)
11.09.08
Alternative Splicing Regulates Activation-Induced Cytidine Deaminase (AID): Implications for Suppression of AID Mutagenic Activity in Normal and Malignant B-Cells Blood First Edition Paper, prepublished online August 5, 2008; DOI 10.1182/blood-2008-03-145995(Vasco)
17.07.2008
They are all about miRNA-155 that acts on AID (Sorry for being chosen on such short notice,no worries about reading, I'm not shure I'll read myself*ok ok, just joking*)Nussenzweig et al. Complementary: Desiderio STeng et al.
08.07.2008
Ferwerda, 2007Directed Evolution 1Directed Evoltution 2(Vasco)
03.07.08
Immortal Strand - review 1Immortal strand - review 2(Vasco)
8:30, 26.06.08
Nature. 2007 Sep 13;449(7159):238-42.Linkand Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Kiel MJ, He S, Ashkenazi R, Gentry SN, Teta M, Kushner JA, Jackson TL, Morrison SJ.Schlimgen, 2008 (Vasco)
8:30 AM, 19.06.08
Gimerlbrant, 2007(Clara - postponed)
8:30 AM, 19.06.08
Pereira, 2003, 20.05.08 (Vasco)Casellas, 1998, 5.06.08 (Vasco) Pancer, 2004 9 AM, 12.06.08 (Vasco)